Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials. Already a member or subscriber? Log in. POEMs patient-oriented evidence that matters are provided by Essential Evidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. Copyright Wiley-Blackwell. Used with permission. Want to use this article elsewhere? Get Permissions. Read the Issue. Sign Up Now. Previous: Testicular Cancer. Feb 15, Issue. Am Fam Physician.
Clinical Question Do oral corticosteroids relieve pain in patients with acute sore throat? Synopsis To determine whether an oral corticosteroid aids in symptom resolution, these researchers searched four databases, including Cochrane Central, trial registries, and reference lists of retrieved studies, and identified 10 studies with a total of 1, patients five years or older.
Read the full article. However, corticosteroids are unlikely to reduce recurrence or relapse of symptoms or days missed from school or work moderate-quality evidence. A single dose of corticosteroids is not likely to cause serious adverse effects moderate-quality evidence. The panel was less confident about whether corticosteroids reduced antibiotic use or the average time to complete resolution of pain low-quality evidence.
Corticosteroids are typically given as 10 mg of dexamethasone for adults 0. The risks may outweigh the benefits when larger doses are given to patients with multiple episodes of sore throat. To mitigate this issue, clinicians should administer the medication in the office, if possible, or prescribe only one dose per visit. Editor's Note: The role of shared decision making cannot be overemphasized.
A single dose of corticosteroids may seem harmless, but this may not be the case for cumulative use. We have to ask ourselves and our patients how much they will benefit if there are no fewer days missed from school or work. Guideline developed by participants without relevant financial ties to industry?
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